5-fluorouracil: An anticancer drug, See: Fluorouracil.
5-FU: 5-fluorouracil, an anticancer drug. See: Fluorouracil.
Abnormal: Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer ).
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Acetate: A molecular ion derived from acetic acid. The formula of acetate is CH3COO-.
Achromycin: See: Tetracycline.
Acne: Localized skin inflammation as a result of overactivity of the oil glands at the base of hair follicles. Acne happens when oil (sebaceous) glands come to life around puberty, when these glands are stimulated by male hormones that are produced in the adrenal glands of both boys and girls.
See the entire definition of Acne
Actinic: Referring to the ultraviolet (UV) rays from sunlight and UV lamps. Sunburn is an actinic burn. An actinic keratosis is a skin lesion that is the consequence of chronic sun exposure. From the Greek "aktis" meaning "ray."
Actinic keratosis: A small rough spot on skin chronically exposed to the sun, precancerous , can develop into a skin cancer called squamous cell carcinoma , a process that typically takes years. Actinic keratoses occur most frequently in fair-skinned people. Common locations are the face, scalp, back of the neck, upper chest, forearm and back of the hand.
See the entire definition of Actinic keratosis
Acute: Of abrupt onset, in reference to a disease. Acute often also connotes an illness that is of short duration, rapidly progressive, and in need of urgent care.
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Aerosol: 1. In general, a fine mist or spray which contains minute particles.
2. In medicine, a spray administered by a nebulizer and inhaled for treatment.
3. In medicine, a mist that causes disease as, for example, the hantavirus pulmonary syndrome.
4. In the environment, particles emitted into the air naturally as in volcanic eruptions and through human action such as burning fossil fuel.
5. In the environment, the pressurized gas used to propel substances out of a container.
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Alcoholism: Physical dependence on alcohol to the extent that stopping alcohol use will bring on withdrawal symptoms. In popular and therapeutic parlance, the term may also be used to refer to ingrained drinking habits that cause health or social problems. Treatment requires first ending the physical dependence, then making lifestyle changes that help the individual avoid relapse . In some cases, medication or hospitalization are needed. Alcohol dependence can have many serious effects on the brain , liver , and other organs of the body.
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Aleve: See: Naproxen.
Allergic reaction: The hypersensitive response of the immune system of an allergic individual to a substance.
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Allergy : A misguided reaction to foreign substances by the immune system , the body system of defense against foreign invaders, particularly pathogens (the agents of infection ). The allergic reaction is misguided in that these foreign substances are usually harmless. The substances that trigger allergy are called allergen. Examples include pollens , dust mite, molds , danders , and certain foods. People prone to allergies are said to be allergic or atopic .
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Alprazolam: A benzodiazepine sedative that causes dose-related depression of the central nervous system. Alprazolam is useful in treating anxiety, panic attacks, insomnia, and muscle spasms. The brand name is Xanax. A generic version is available.
Amebiasis: Infection of the intestines with amebae, especially with the ameba Entamoeba histolytica, characterized by frequent, loose stools flecked with blood and mucus.
Amitriptyline: An antidepressant medication. In some patients with depression, abnormal levels of brain chemicals called neurotransmitters may relate to the depression. Amitriptyline elevates mood by raising the level of neurotransmitters in brain tissue. Amitriptyline is also a sedative that is useful for depressed patients with insomnia, restlessness, and nervousness. It is sometimes used to treat fibromyalgia and symptoms related to chronic pain. Brand names are Elavil and Endep. A generic version is available.
Anaprox: See: Naproxen.
Anesthetic: A substance that causes lack of feeling or awareness. A local anesthetic causes loss of feeling in a part of the body. A general anesthetic puts the person to sleep.
Angina: Chest pain due to an inadequate supply of oxygen to the heart muscle. The chest pain of angina is typically severe and crushing. There is a feeling just behind the breastbone (the sternum) of pressure and suffocation.
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Anorexia: An eating disorder characterized by markedly reduced appetite or total aversion to food. Anorexia is a serious psychological disorder. It is a condition that goes well beyond out-of-control dieting. The person with anorexia, most often a girl or young woman, initially begins dieting to lose weight. Over time, the weight loss becomes a sign of mastery and control. The drive to become thinner is thought to be secondary to concerns about control and fears relating to one's body. The individual continues the endless cycle of restrictive eating, often to a point close to starvation. This becomes an obsession and is similar to an addiction to a drug. Anorexia can be life-threatening. Also called anorexia nervosa.
Anti-infective: Something capable of acting against infection, by inhibiting the spread of an infectious agent or by killing the infectious agent outright.
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Antigen: A substance that is capable of causing the production of an antibody .
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Antihistamines: Drugs that combat the histamine released during an allergic reaction by blocking the action of the histamine on the tissue. Antihistamines do not stop the formation of histamine nor do they stop the conflict between the IgE and antigen. Therefore, antihistamines do not stop the allergic reaction but protect tissues from some of its effects. Antihistamines frequently cause mouth dryness and sleepiness. Newer "non sedating" antihistamines are generally thought to be somewhat less effective. Antihistamine side effects that very occasionally occur include urine retention in males and fast heart rate.
Antiseptic: Something that discourages the growth microorganisms. By contrast, aseptic refers to the absence of microorganisms.
Anxiety: A feeling of apprehension and fear characterized by physical symptoms such as palpitations , sweating, and feelings of stress . Anxiety disorders are serious medical illnesses that affect approximately 19 million American adults. These disorders fill people's lives with overwhelming anxiety and fear. Unlike the relatively mild, brief anxiety caused by a stressful event such as a business presentation or a first date, anxiety disorders are chronic, relentless, and can grow progressively worse if not treated.
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Appendix: A small outpouching from the beginning of the large intestine (the ascending colon ). Formally called the vermiform appendix because it was thought to be wormlike.
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Arms: An appendage in anatomy and in clinical trials. See: Arm.
Arrhythmia: An abnormal heart rhythm.
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Arthritis: Inflammation of a joint. When joints are inflamed they can develop stiffness, warmth, swelling, redness and pain. There are over 100 types of arthritis. (see osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, lupus, gout, pseudogout).
Bacterial: Of or pertaining to bacteria. For example, a bacterial lung infection.
Baldness: Medically known as alopecia. There are many types of baldness, each with a different cause. Baldness may be localized to the front and top of the head, as in the very common type of male-pattern baldness; baldness may be patchy, a condition called alopecia areata; or it may involve the entire head, as in alopecia capitis totalis. The word "alopecia" comes from the Greek "alopex" for "fox." Foxes are less furry when afflicted with a skin disease called the "mange" which causes them to lose their hair. When a fancier word for "baldness" was sought, the mangy fox supplied it, "alopecia" or, if you wish, "fox-mange", not a very positive image to associate with baldness!
Birth control : Birth control is the use of any practices, methods, or devices to prevent pregnancy from occurring in a sexually active woman. Also referred to as family planning, pregnancy prevention, fertility control, or contraception; birth control methods are designed either to prevent fertilization of an egg or implantation of a fertilized egg in the uterus.
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Blister: A collection of fluid underneath the top layer of skin (epidermis). One that is more than 5 mm in diameter with thin walls and is full of watery fluid is called a bulla or a bleb. There are many causes of blisters including burns , vesicant agents, friction forces, and diseases of the skin.
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Blood pressure: The blood pressure is the pressure of the blood within the arteries. It is produced primarily by the contraction of the heart muscle. It's measurement is recorded by two numbers. The first (systolic pressure) is measured after the heart contracts and is highest. The second (diastolic pressure) is measured before the heart contracts and lowest. A blood pressure cuff is used to measure the pressure. Elevation of blood pressure is called "hypertension".
Breast cancer: Breast cancer is diagnosed with self- and physician-examination of the breasts, mammography, ultrasound testing, and biopsy. There are many types of breast cancer that differ in their capability of spreading to other body tissues (metastasis). Treatment of breast cancer depends on the type and location of the breast cancer, as well as the age and health of the patient. The American Cancer Society recommends that a woman should have a baseline mammogram between the ages of 35 and 40 years. Between 40 and 50 years of age mammograms are recommended every other year. After age 50 years, yearly mammograms are recommended.
Bullae: More than one bulla, a bulla being a blister more than 5 mm (about 3/16 inch) in diameter with thin walls that is full of fluid.
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Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread).
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Carcinoma: Cancer that begins in the skin or in tissues that line or cover body organs. For example, carcinoma can arise in the breast , colon, liver, lung, prostate, and stomach.
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Cardiac: Having to do with the heart.
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Chemotherapy : 1. In the original sense, a chemical that binds to and specifically kills microbes or tumor cells. The term chemotherapy was coined in this regard by Paul Ehrlich (1854-1915).
2. In oncology, drug therapy for cancer. Also called "chemo" for short.
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Chlortetracycline: The first drug of the tetracycline family, to be introduced (in 1948). For more information, see: Tetracycline.
Cholesterol: The most common type of steroid in the body, cholesterol has gotten something of a bad name. However, cholesterol is a critically important molecule.
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Choriocarcinoma: A highly malignant tumor that arises from trophoblastic cells within the uterus. Choriocarcinoma tends to be invasive and to metastasize early and widely through both the venous and lymphatic systems. Choriocarcinoma is one of the two types of gestational trophoblastic tumor, the other being hydatidiform mole.
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Chronic: This important term in medicine comes from the Greek chronos, time and means lasting a long time.
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Conditioning: 1) Exercise and practice to build the body up for either improved normal performance, as in physical therapy, or in preparation for sports performance. 2) A method of educating involving repetitive activities to influence behavior.
Congestive heart failure : Inability of the heart to keep up with the demands on it and, specifically, failure of the heart to pump blood with normal efficiency. When this occurs, the heart is unable to provide adequate blood flow to other organs such as the brain, liver and kidneys. Heart failure may be due to failure of the right or left or both ventricles. The signs and symptoms depend upon which side of the heart is failing. They can include shortness of breath (dyspnea), asthma due to the heart (cardiac asthma), pooling of blood (stasis) in the general body (systemic) circulation or in the liver's (portal) circulation, swelling ( edema ), blueness or duskiness (cyanosis), and enlargement (hypertrophy) of the heart.
See the entire definition of Congestive heart failure
Cutaneous: Relating to the skin. As, for example, in cutaneous allodynia, a cutaneous papilloma, and cutaneous syndactyly. From the Latin cutis meaning skin.
Depression : An illness that involves the body, mood, and thoughts, that affects the way a person eats and sleeps, the way one feels about oneself, and the way one thinks about things. A depressive disorder is not the same as a passing blue mood. It is not a sign of personal weakness or a condition that can be wished away. People with a depressive disease cannot merely "pull themselves together" and get better. Without treatment, symptoms can last for weeks, months, or years. Appropriate treatment, however, can help most people with depression.
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Dermatologist: A doctor who specializes in the diagnosis and treatment of skin problems.
Desquamation: The shedding of the outer layers of the skin. For example, once the rash of measles fades, there is desquamation. The word comes from the Latin "desquamare" meaning "to scrape the scales off a fish."
Diabetes: Refers to diabetes mellitus or, less often, to diabetes insipidus . Diabetes mellitus and diabetes insipidus share the name "diabetes" because they are both conditions characterized by excessive urination (polyuria).
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Diagnosis: 1 The nature of a disease ; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies . 3 The identification of any problem. The diagnosis was a plugged IV.
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Diethylstilbestrol: The earliest synthetic (man-made) form of the hormone estrogen .
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Diuretic: Anything that promotes the formation of urine by the kidney. (The word "diuretic" comes from a combination of the Greek "dia-", thoroughly + "ourein", to urinate = to urinate thoroughly).
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Doxycycline : Brand name: Vibramycin. A synthetic broad-spectrum antibiotic derived from tetracycline . Doxycycline is used for many different types of infections, including respiratory tract infections due to Hemophilus influenzae, Streptococcus pneumoniae, or Mycoplasma pneumoniae. It is also used for the treatment of nongonococcal urethritis (due to Ureaplasma), Rocky Mountain spotted fever, typhus, chancroid, cholera , brucellosis, syphilis, and acne .
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Dynacin: Brand name for minocycline.
Ear: The hearing organ. There are three sections of the ear, according to the anatomy textbooks. They are the outer ear (the part we see along the sides of our head behind the temples), the middle ear, and the inner ear. But in terms of function, the ear has four parts: those three and the brain. Hearing thus involves all parts of the ear as well as the auditory cortex of the brain. The external ear helps concentrate the vibrations of air on the ear drum and make it vibrate. These vibrations are transmitted by a chain of little bones in the middle ear to the inner ear. There they stimulate the fibers of the auditory nerve to transmit impulses to the brain.
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Eczema: A particular type of inflammatory reaction of the skin in which there are typically vesicles (tiny blister-like raised areas) in the first stage followed by erythema (reddening), edema (swelling), papules (bumps), and crusting of the skin followed, finally, by lichenification (thickening) and scaling of the skin. Eczema characteristically causes itching and burning of the skin.
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Edema: The swelling of soft tissues as a result of excess water accumulation.
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Elavil: See: Amitriptyline.
Endep: See: Amitriptyline.
Endometriosis: In endometriosis , cells that normally grow inside the uterus (womb), instead grow outside the uterus.
See the entire definition of Endometriosis
Epilepsy (seizure disorder): When nerve cells in the brain fire electrical impulses at a rate of up to four times higher than normal, this causes a sort of electrical storm in the brain, known as a seizure. A pattern of repeated seizures is referred to as epilepsy. Known causes include head injuries, brain tumors, lead poisoning, maldevelopment of the brain, genetic and infectious illnesses. But in fully half of cases, no cause can be found. Medication controls seizures for the majority of patients.
Erythema: A redness of the skin resulting from inflammation, for example, as caused by sunburn.
Estrogen: Estrogen is a female hormone produced by the ovaries. Estrogen deficiency can lead to osteoporosis .
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Estrogens: Female hormones produced by the ovaries. Estrogen deficiency can lead to osteoporosis .
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Expectorant: A medication that helps bring up mucus and other material from the lungs, bronchi, and trachea. An example of as expectorant is guaifenesin which promotes drainage of mucus from the lungs by thinning the mucus and also lubricates the irritated respiratory tract. Sometimes the term "expectorant" is incorrectly extended to any cough medicine. From the Latin expectorare, to expel from the chest, from ex-, out of + pectus, chest.
Fever : Although a fever technically is any body temperature above the normal of 98.6 degrees F. (37 degrees C.), in practice a person is usually not considered to have a significant fever until the temperature is above 100.4 degrees F (38 degrees C.).
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Flu: Short for influenza. The flu is caused by viruses that infect the respiratory tract which are divided into three types, designated A, B, and C. Most people who get the flu recover completely in 1 to 2 weeks, but some people develop serious and potentially life-threatening medical complications, such as pneumonia. Much of the illness and death caused by influenza can be prevented by annual influenza vaccination.
Fluorouracil: A much-used anticancer drug that belongs to the family of drugs called antimetabolites . Full name: 5-fluorouracil. Abbreviation: 5-FU .
See the entire definition of Fluorouracil
Fungal: Pertaining to a fungus. For example, a fungal skin infection.
Fungus: A single-celled or multicellular organism. Fungi can be true pathogens (such as histoplasmosis and coccidioidomycosis) that cause infections in healthy persons or they can be opportunistic pathogens (such as aspergillosis, candidiasis, and cryptococcosis) that cause infections in immunocompromised persons (including cancer patients, transplant recipients, and persons with AIDS). An example of a common fungus is the yeast organism which causes thrush and diaper rash (diaper dermatitis). Fungi are also used for the development of antibiotics, antitoxins, and other drugs used to control various human diseases.
Generic: 1. The chemical name of a drug. 2. A term referring to the chemical makeup of a drug rather than to the advertised brand name under which the drug may be sold. 3.A term referring to any drug marketed under its chemical name without advertising.
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Genitalia: The male and female reproductive organs. The genitalia include internal structures such as the ovary, and external structures such as the penis. See also: Female organs of reproduction; Male organs of reproduction.
Glaucoma : A common eye condition in which the fluid pressure inside the eyes rises because of slowed fluid drainage from the eye. If untreated, it may damage the optic nerve and other parts of the eye, causing the loss of vision or even blindness.
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Gonorrhea: A sexually transmitted infection (STI) caused by the bacterium Neisseria gonorrhoea. Although gonorrhea is known primarily as a sexually transmitted infection (STI), it is not exclusively so, but can also be transmitted to the newborn during the birthing process.
See the entire definition of Gonorrhea
Gram-negative: Gram-negative bacteria lose the crystal violet stain (and take the color of the red counterstain) in Gram's method of staining. This is characteristic of bacteria that have a cell wall composed of a thin layer of a particular substance (called peptidoglycan).
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Gram-positive: Gram-positive bacteria retain the color of the crystal violet stain in the Gram stain. This is characteristic of bacteria that have a cell wall composed of a thick layer of a particular substance (called peptidologlycan).
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Heart: The muscle that pumps blood received from veins into arteries throughout the body. It is positioned in the chest behind the sternum (breastbone; in front of the trachea, esophagus, and aorta; and above the diaphragm muscle that separates the chest and abdominal cavities. The normal heart is about the size of a closed fist, and weighs about 10.5 ounces. It is cone-shaped, with the point of the cone pointing down to the left. Two-thirds of the heart lies in the left side of the chest with the balance in the right chest.
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Heart failure : Inability of the heart to keep up with the demands on it and, specifically, failure of the heart to pump blood with normal efficiency. When this occurs, the heart is unable to provide adequate blood flow to other organs such as the brain, liver and kidneys. Heart failure may be due to failure of the right or left or both ventricles. The signs and symptoms depend upon which side of the heart is failing. They can include shortness of breath (dyspnea), asthma due to the heart (cardiac asthma), pooling of blood (stasis) in the general body (systemic) circulation or in the liver's (portal) circulation, swelling ( edema ), blueness or duskiness (cyanosis), and enlargement (hypertrophy) of the heart.
See the entire definition of Heart failure
Hemorrhoid: A dilated (enlarged) vein in the walls of the anus and sometimes around the rectum , usually caused by untreated constipation but occasionally associated with chronic diarrhea .
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Herbal: 1. An adjective, referring to herbs, as in an herbal tea.
2. A noun, usually reflecting the botanical or medicinal aspects of herbs; also a book which catalogs and illustrates herbs.
The word "herbal" was pronounced with a silent "h" on both sides of the Atlantic until the 19th century but this usage persists only on the American side.
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Herbal remedy: A medication prepared from plants, including most of the world's traditional remedies for disease. Most people think of herbal remedies as products sold over the counter as "supplements", such as saw palmetto extract or goldenseal ointment. However, many over- the-counter and prescription drugs are based on ingredients originally derived from plants, including aspirin and digoxin. Lab tests have shown that some herbal remedies are indeed effective against illness. One should use these drugs as carefully as prescription medicines, taking care to avoid overdose, interactions with other medications, and misuse.
High blood pressure : Also known as hypertension, high blood pressure is, by definition, a repeatedly elevated blood pressure exceeding 140 over 90 mmHg -- a systolic pressure above 140 with a diastolic pressure above 90.
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Hurricane: A regionally specific name for a strong tropical cyclone. The term hurricane applies in the North Atlantic Ocean, the Northeast Pacific Ocean east of the dateline, or the South Pacific Ocean east of 160E.
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Hyperpigmentation: Dark spots on the skin. Hyperpigmentation is primarily a cosmetic concern that can be covered with make-up, although in some cases (such as the café au lait spots associated with neurofibromatosis) it can be a sign of an underlying medical problem. If treatment of hyperpigmentation is desired, a dermatologist may be able to use dermabrasion, laser treatments, or bleaching agents to effect change.
Hypertension: High blood pressure , defined as a repeatedly elevated blood pressure exceeding 140 over 90 mmHg -- a systolic pressure above 140 with a diastolic pressure above 90.
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Ibuprofen: A non-steroidal anti-inflammatory drug (NSAID) commonly used to treat pain, swelling, and fever. Common brand names for Ibuprofen include Advil, Motrin, and Nuprin.
Immune: Protected against infection. The Latin immunis means free, exempt.
Immune system: A complex system that is responsible for distinguishing us from everything foreign to us, and for protecting us against infections and foreign substances. The immune system works to seek and kill invaders.
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Inflammation: A basic way in which the body reacts to infection , irritation or other injury, the key feature being redness, warmth, swelling and pain . Inflammation is now recognized as a type of nonspecific immune response .
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Influenza: The flu is caused by viruses that infect the respiratory tract which are divided into three types, designated A, B, and C. Most people who get the flu recover completely in 1 to 2 weeks, but some people develop serious and potentially life-threatening medical complications, such as pneumonia. Much of the illness and death caused by influenza can be prevented by annual influenza vaccination.
Insomnia: The perception or complaint of inadequate or poor-quality sleep because of one or more of the following: difficulty falling asleep; waking up frequently during the night with difficulty returning to sleep; waking up too early in the morning; or unrefreshing sleep. Insomnia is not defined by the number of hours of sleep a person gets or how long it takes to fall asleep. Individuals vary normally in their need for, and their satisfaction with, sleep. Insomnia may cause problems during the day, such as tiredness, a lack of energy, difficulty concentrating, and irritability.
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Intensive care: See critical care.
Interferon : A naturally occurring substance that interferes with the ability of viruses to reproduce. Interferon also boosts the immune system.
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Intractable: Unstoppable. For example, intractable diarrhea or intractable pain.
Itching: An uncomfortable sensation in the skin that feels as if something is crawling on the skin or in the skin, and makes the person want to scratch the affected area.
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Keratosis: A localized horny overgrowth of the upper layer of skin such as a callus or wart. Among the common forms of keratosis are actinic keratosis and senile keratosis.
See the entire definition of Keratosis
Kidney: One of a pair of organs located in the right and left side of the abdomen which clear "poisons" from the blood, regulate acid concentration and maintain water balance in the body by excreting urine. The kidneys are part of the urinary tract. The urine then passes through connecting tubes called "ureters" into the bladder. The bladder stores the urine until it is released during urination.
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Leprosy: See: Hansen disease.
Leukemia : Cancer of the blood cells. The growth and development of the blood cells are abnormal. Strictly speaking, leukemia should refer only to cancer of the white blood cells (the leukocytes) but in practice it can apply to malignancy of any cellular element in the blood or bone marrow, as in red cell leukemia (erythroleukemia).
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Levonorgestrel: A progestin. Named levonorgestrel because it is the levorotatory form of norgestrel. Used in combination with an estrogen as an oral contraceptive. Used alone for emergency contraceptive (in Plan B) and the treatment of menstrual disorders or endometriosis.
Lips: Aside from the lips of the mouth, there are two pairs of lips at the entrance to the vagina. They are the labia majora (the larger outside pair) and the labia minora (the smaller inside pair). Together they form part of the vulva (the female external genitalia).
Lubricant: An oily or slippery substance. A vaginal lubricant may be helpful for women who feel pain during intercourse because of vaginal dryness.
Lymphatic: 1. One of the lymphatics, vessel that convey the lymph fluid. 2. Pertaining to the lymph, lymphoid tissue, or lymphocytes. 3. Lacking energy. Sluggish.
From the Latin lympha (water or water goddess), from the Greek nymphe (nymph).
Lymphoma: Tumor of the lymphoid tissue. Diagnosis is by biopsy. Treatment may be chemotherapy, radiation, surgery, or medication, depending on the age of the patient and type of tumor.
Malaria : An infectious disease caused by protozoan parasites from the Plasmodium family that can be transmitted by the sting of the Anopheles mosquito or by a contaminated needle or transfusion. Falciparum malaria is the most deadly type.
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Malignant: 1. Tending to be severe and become progressively worse, as in malignant hypertension. 2. In regard to a tumor, having the properties of a malignancy that can invade and destroy nearby tissue and that may spread (metastasize) to other parts of the body.
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Manic: Refers to a mood disorder in which a person seems "high", euphoric, expansive, sometimes agitated, hyperexcitable, with flights of ideas and speech.
Melanoma : The most dangerous form of skin cancer, a malignancy of the melanocyte, the cell that produces pigment in the skin. Melanoma is most common in people with fair skin, but can occur in people with all skin colors. Most melanomas present as a dark, mole-like spot that spreads and, unlike a mole, has an irregular border. The tendency toward melanoma may be inherited, and the risk increases with overexposure to the sun and sunburn.
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Menopause : The time in a woman's life when menstrual periods permanently stop; it is also called the "change of life." Menopause is the opposite of the menarche.
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Menstruation: The periodic blood that flows as a discharge from the uterus. Also called menorrhea, the time during which menstruation occurs is referred to as menses. The menses occurs at approximately 4 week intervals to compose the menstrual cycle.
Methotrexate : A drug that acts as an antimetabolite and specifically as a folic acid antagonist that inhibits the synthesis of DNA , RNA , and protein .
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Minocin: Brand name for minocycline.
Minocycline: A tetracycline antibiotic used to treat many different bacteria in urinary tract infections, acne , gonorrhea , and chlamydia , and other injections. The brand names for minocycline include Dynacin, Minocin, and Vectrin.
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Motion sickness : Motion sickness is a very common disturbance of the inner ear that is caused by repeated motion such as from the swell of the sea, the movement of a car, the motion of a plane in turbulent air, etc. In the inner ear (which is also called the labyrinth), motion sickness affects the sense of balance and equilibrium and, hence, the sense of spatial orientation.
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Mountain sickness: Also known as altitude sickness or altitude illness, this is a disorder caused by being at high altitude, commonly above 8,000 feet (2,440 meters).
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Mouth: 1. The upper opening of the digestive tract, beginning with the lips and containing the teeth, gums, and tongue. Foodstuffs are broken down mechanically in the mouth by chewing and saliva is added as a lubricant. Saliva contains amylase, an enzyme that digests starch. 2. Any opening or aperture in the body. The mouth in both senses of the word is also called the os, the Latin word for an opening, or mouth. The o in os is pronounced as in hope. The genitive form of os is oris from which comes the word oral.
MPH: Master of Public Health (a master's degree in this field of medicine).
Multiple sclerosis : Abbreviated MS. A disease of the central nervous system (CNS) marked by numbness, weakness, loss of muscle coordination, and problems with vision, speech, and bladder control. MS is an autoimmune disease in which the body's immune system attacks myelin, a key substance that serves as a nerve insulator and helps in the transmission of nerve signals. The progress, severity and specific symptoms in MS are unpredictable. One never knows when attacks will occur, how long they will last, or how severe they will be. Most people with MS are between the ages of 20 and 40 at the time of diagnosis. The term "multiple" refers to the multiple places in the CNS that are affected and to the multiple relapses and remissions characteristic of MS.
See the entire definition of Multiple sclerosis
Muscle: Muscle is the tissue of the body which primarily functions as a source of power. There are three types of muscle in the body. Muscle which is responsible for moving extremities and external areas of the body is called "skeletal muscle." Heart muscle is called "cardiac muscle." Muscle that is in the walls of arteries and bowel is called "smooth muscle."
Naprelan: See: Naproxen.
Naprosyn: See: Naproxen.
Naproxen : A non-steroidal anti-inflammatory drug (NSAID) used for the management of mild to moderate pain, fever, and inflammation . Naproxen blocks the enzyme cyclooxygenase that makes prostaglandins, resulting in lower concentrations of prostaglandins. As a consequence, inflammation, pain and fever are reduced. Brand names for naproxen include Anaprox, Naprelan, Naprosyn, and Aleve.
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Nausea: Nausea, is the urge to vomit. It can be brought by many causes including, systemic illnesses, such as influenza, medications, pain, and inner ear disease. When nausea and/or vomiting are persistent, or when they are accompanied by other severe symptoms such as abdominal pain, jaundice, fever, or bleeding, a physician should be consulted.
New England Journal of Medicine: Despite its regional name, The New England Journal of Medicine (NEJM) is far from provincial. It is an eminent weekly national and international general medical journal, devoted to no single specialty, but to all of medicine. The Journal is published by the Massachusetts Medical Society and is closely associated with the medical schools (Boston University, Harvard and Tufts) in the Boston area.
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Nodular: Bumpy.
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Nose: The external midline projection from the face.
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Ointment: A medication preparation that is applied topically (onto the skin). An ointment has an oil base whereas a cream is water-soluble. (The word ointment comes from the Latin ungere meaning anoint with oil).
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Onset: In medicine, the first appearance of the signs or symptoms of an illness as, for example, the onset of rheumatoid arthritis . There is always an onset to a disease but never to the return to good health. The default setting is good health.
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Oral contraceptive: A birth control pill taken by mouth. Most oral contraceptives include both estrogen and progesterone. When given in certain amounts and at certain times in the menstrual cycle, these hormones prevent the ovary from releasing an egg for fertilization.
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Osteoporosis: Thinning of the bones with reduction in bone mass due to depletion of calcium and bone protein . Osteoporosis predisposes a person to fractures, which are often slow to heal and heal poorly. It is more common in older adults, particularly post-menopausal women; in patients on steroids; and in those who take steroidal drugs. Unchecked osteoporosis can lead to changes in posture , physical abnormality (particularly the form of hunched back known colloquially as " dowager's hump "), and decreased mobility.
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Ovarian: Of or pertaining to the ovary.
Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia . Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
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Parkinson's disease: See: Parkinson disease.
Pediatric: Pertaining to children.
Petit mal: A form of epilepsy with very brief, unannounced lapses in consciousness. A petit mal seizure involves a brief loss of awareness, which can be accompanied by blinking or mouth twitching. Petit mal seizures have a very characteristic appearance on an electroencephalogram (EEG).
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Phosphate: A form of phosphoric acid. Calcium phosphate makes bones and teeth hard.
Photodynamic therapy: A form of cancer treatment using an photosensitizing agent administered intravenously which concentrates selectively in tumor cells, followed by exposure of the tumor tissue to a special red laser light, in order to destroy as much of the tumor as possible.
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Photosensitivity: In medicine, increased sensitivity of the skin to light and other sources of UV. Photosensitivity commonly causes reddening and blistering of the skin with exposure to sunlight and, in time, it heightens the risk of skin cancer. A number of diseases make for photosensitivity, as do scores of prescription and non-prescription drugs. (For details, see Sunburn and Sun-Sensitizing Drugs ).
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Pigmentation: The coloring of the skin, hair, mucous membranes, and retina of the eye.
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Poison: Any substance that can cause severe distress or death if ingested, breathed in, or absorbed through the skin. Many substances that normally cause no problems, including water and most vitamins, can be poisonous if taken in too large of a quantity. Poison treatment depends on the substance: if there are treatment instructions on the substance's container and you are sure it contained no other item, follow those directions immediately. Always contact your nearest Poison Control Center if you are concerned about possible poison ingestion.
Poison ivy : Skin inflammation resulting from contact with oils from the poison ivy vine. Chemicals produced by this vine cause an immune reaction, producing redness, itching, and blistering of the skin.
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Poly-: 1) Prefix meaning much or many For example, polycystic means characterized by many cysts. 2) Short form for polymorphonuclear leukocyte, a type of white blood cell.
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Porphyria: A diverse group of diseases in which the production of heme is disrupted. Porphyria is derived from the Greek word "porphyra", which means purple. When heme production is faulty, porphyrins are overproduced and lend a reddish-purple color to urine. All forms of porphyrias are inherited. The key clinical features are skin sensitivity to sunlight and/or by intermittent acute attacks of abdominal and nerve pain.
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Potassium: The major positive ion (cation) found inside of cells. The chemical notation for potassium is K+.
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Prostate: A gland within the male reproductive system that is located just below the bladder. Chestnut shaped, the prostate surrounds the beginning of the urethra, the canal that empties the bladder.
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Prostate cancer: An uncontrolled (malignant) growth of cells in the prostate gland which is located at the base of the urinary bladder and is responsible for helping control urination as well as forming part of the semen. Prostate cancer is the second leading cause of death of males in the U.S.
Pruritus: Itching. Pruritus can result from drug reaction, food allergy, kidney or liver disease, cancers, parasites, aging or dry skin, contact skin reaction, such as poison ivy, and for unknown reasons.
Psoriasis : A reddish, scaly rash often located over the surfaces of the elbows, knees, scalp, and around or in the ears, navel, genitals or buttocks. Psoriasis is an autoimmune disease that is mediated by T lymphocytes. It is also a very common disease, Chronic plaque psoriasis affects approximately 2% of people around the world. About 10-15% of patients with psoriasis develop joint inflammation (inflammatory arthritis ). Treatment options include topical steroid creams, tar soap preparations, and exposure to ultraviolet light.
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Psychiatric: Pertaining to or within the purview of psychiatry , the medical specialty concerned with the prevention, diagnosis , and treatment of mental illness.
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Quinine: The original antimalarial agent, quinine took its name from the Peruvian Indian word "kina" meaning "bark of the tree" referring to the cinchona tree. From this tree, quinine was first obtained. The Peruvian Indians called it "the fever tree."
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Radiation: 1. Rays of energy. Gamma rays and X-rays are two of the types of energy waves often used in medicine. 2. The use of energy waves to diagnose or treat disease. See also: Irradiation.
Recur: To occur again. To return. Any symptom (such as fatigue), any sign (such as a heart murmur), or any disease can recur.
Remedy: Something that consistently helps treat or cure a disease . From the Latin "remedium" meaning that which heals again (and again).
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Resolution: In genetics , resolution refers to the degree of molecular detail on a physical map of DNA , ranging from low to high.
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Respiratory: Having to do with respiration, the exchange of oxygen and carbon dioxide. From the Latin re- (again) + spirare (to breathe) = to breathe again.
Rheumatoid arthritis : An autoimmune disease which causes chronic inflammation of the joints, the tissue around the joints, as well as other organs in the body. Autoimmune diseases occur when the body tissues are mistakenly attacked by its own immune system. The immune system is a complex organization of cells and antibodies designed normally to "seek and destroy" invaders of the body, particularly infections. Patients with these diseases have antibodies in their blood which target their own body tissues, where they can be associated with inflammation. Because it can affect multiple other organs of the body, rheumatoid arthritis is referred to as a systemic illness and is sometimes called rheumatoid disease. While rheumatoid arthritis is a chronic illness (meaning it can last for years) patients may experience long periods without symptoms.
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Schizophrenia : One of several brain diseases whose symptoms that may include loss of personality (flat affect), agitation, catatonia, confusion, psychosis , unusual behavior, and withdrawal. The illness usually begins in early adulthood.
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Sclerosis: Localized hardening of skin.
Sensation: In medicine and physiology , sensation refers to the registration of an incoming ( afferent ) nerve impulse in that part of the brain called the sensorium , which is capable of such perception. Therefore, the awareness of a stimulus as a result of its perception by sensory receptors. (Sensory is here synonymous with sensation.)
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Sensitivity: 1. In psychology, the quality of being sensitive. As, for example, sensitivity training, training in small groups to develop a sensitive awareness and understanding of oneself and of ones relationships with others. 2. In disease epidemiology, the ability of a system to detect epidemics and other changes in disease occurrence. 3. In screening for a disease, the proportion of persons with the disease who are correctly identified by a screening test. 4. In the definition of a disease, the proportion of persons with the disease who are correctly identified by defined criteria.
Sinus: 1. An air-filled cavity in a dense portion of a skull bone. The sinuses decrease the weight of the skull. The sinuses are formed in four right-left pairs. The frontal sinuses are positioned behind the forehead, while the maxillary sinuses are behind the cheeks. The sphenoid and ethmoid sinuses are deeper in the skull behind the eyes and maxillary sinuses. The sinuses are lined by mucous-secreting cells. Air enters the sinuses through small opening in bone called ostia. If an ostium is blocked, air cannot pass into the sinus and likewise mucous cannot drain out. See also: Sinusitis .
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Sleep : The body's rest cycle.
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Sodium: The major positive ion (cation) in fluid outside of cells. The chemical notation for sodium is Na+. When combined with chloride, the resulting substance is table salt.
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Spasticity: A state of increased tone of a muscle (and an increase in the deep tendon reflexes). For example, with spasticity of the legs (spastic paraplegia) there is an increase in tone of the leg muscles so they feel tight and rigid and the knee jerk reflex is exaggerated.
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SPF (sun protection factor): A number on a scale for rating sunscreens. SPF stands for Sun Protection Factor.
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Squamous-cell carcinoma: See: Squamous cell carcinoma.
Steroid: A general class of chemical substances that are structurally related to one another and share the same chemical skeleton (a tetracyclic cyclopenta[a]phenanthrene skeleton).
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Sulfonamides: The sulfa-related group of antibiotics, which are used to treat bacterial infection and some fungal infections.
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Sumycin: See: Tetracycline.
Sunburn: Sunburn is an inflammation of the skin that develops in response to exposure to ultraviolet (UV) radiation from the sun or from tanning beds and booths that emit UV radiation . Sunburn is manifested by reddened, painful skin that may develop blisters.
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Sunscreen: A substance that blocks the effect of the sun's harmful rays. Using lotions that contain sunscreens can reduce the risk of skin cancer, including melanoma.
Surgery: The word "surgery" has multiple meanings. It is the branch of medicine concerned with diseases and conditions which require or are amenable to operative procedures. Surgery is the work done by a surgeon. By analogy, the work of an editor wielding his pen as a scalpel is s form of surgery. A surgery in England (and some other countries) is a physician's or dentist's office.
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Syndrome: A set of signs and symptoms that tend to occur together and which reflect the presence of a particular disease or an increased chance of developing a particular disease.
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Testosterone: A "male hormone" -- a sex hormone produced by the testes that encourages the development of male sexual characteristics, stimulates the activity of the male secondary sex characteristics, and prevents changes in them following castration. Chemically, testosterone is 17-beta-hydroxy-4-androstene-3-one.
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Tetracycline: A family of broad-spectrum antibiotics effective against a remarkably wide variety of organisms. Bacteria susceptible to teracycline include H. flu (Hemophilus influenzae), strep (Streptococcus pneumoniae), Mycoplasma pneumoniae, Chlamydia psittaci, Chlamydia trachomatis , and Neisseria gonorrhoeae (the cause of gonorrhea ). Tetracycline is also used to treat nongonococcal urethritis (due to Ureaplasma), Rocky mountain spotted fever , typhus , chancroid , cholera , brucellosis , anthrax , and syphilis . It is used in combination with other medications to treat Helicobacter pylori , the bacteria associated with ulcers of the stomach and duodenum .
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Therapy: The treatment of disease .
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Tic: A repetitive movement that is difficult, if not impossible, to control. Tics can affect any group of muscles. The most common are facial tics, such as eye- blinking, nose-twitching, or grimacing. Tics that affect the muscles used to produce speech are known as vocal tics, and can range from grunts or whistles to the repetition of complete words or phrases. Complex motor tics involve multiple, sequenced movements, and can include behaviors such as twirling in place, tapping a certain number of times, or stooping to touch the ground. Tics are believed to arise in differences in or damage to the basal ganglia, a structure deep within the brain that controls automatic movements and that also affects impulsivity.
Tic douloureux: A synonym for trigeminal neuralgia. From the French, meaning literally a painful tic. See: Trigeminal neuralgia.
Topical: Pertaining to a particular surface area. A topical agent is applied to a certain area of the skin and is intended to affect only the area to which it is applied. Whether its effects are indeed limited to that area depends upon whether the agent stays where it is put or is absorbed into the blood stream.
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Tourette syndrome : A tic disorder characterized by the presence of chronic vocal and motor tics, probably based on differences in or damage to the basal ganglia of the brain.
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Trichinosis: See: Trichinellosis.
Tuberculosis : A highly contagious infection caused by the bacterium called Mycobacterium tuberculosis. Abbreviated TB. Tubercles (tiny lumps) are a characteristic finding in TB. Diagnosis may be made by skin test, which if positive should will be followed by a chest X-ray to determine the status (active or dormant) of the infection. Tuberculosis is more common in people with immune system problems, such as AIDS, than in the general population. Treatment of active tuberculosis is mandatory by law in the US, and should be available at no cost to the patient through the public health system. It involves a course of antibiotics and vitamins that lasts about six months. It is important to finish the entire treatment, both to prevent reoccurrence and to prevent the development of antibiotic-resistant tuberculosis. Most patients with tuberculosis do not need to be quarantined, but it is sometimes necessary.
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Tylenol: See: Acetaminophen.
Ulcer: An area of tissue erosion, for example, of the skin or lining of the gastrointestinal (GI) tract. Due to the erosion, an ulcer is concave. It is always depressed below the level of the surrounding tissue.
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Ultraviolet A: One of the three types of invisible light rays (together with ultraviolet B and ultraviolet C) given off by the sun.
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Ultraviolet B: One of the three types of invisible light rays (together with ultraviolet A and ultraviolet C) given off by the sun.
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Ultraviolet C: One of the three types of invisible light rays (together with ultraviolet A and ultraviolet B) given off by the sun.
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Ultraviolet radiation: Invisible rays that are part of the energy that comes from the sun. Ultraviolet radiation can burn the skin and cause skin cancer .
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Urinary: Having to do with the kidneys, ureters, and bladder. The urinary system represents the functional and anatomic aspects of the kidneys, ureters, and bladder.
Urinary tract: The organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra.
Uterine bleeding: See: Menstruation. See also Menometrorrhagia; Menorrhagia; Metrorrhagia.
Uterine cancer: Cancer of the womb (the uterus). Also called endometrial cancer . Cancer of the uterus occurs most often in women between the ages of 55 and 70 years. It accounts for about 6% of cancer in women. Women at elevated risk for uterine cancer include those who are obese , who have few or no children, who began menstruating at a young age, who had a late menopause , and women of high socioeconomic status. It is thought that most of these risk factors are related to hormones, especially excess estrogen .
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Vagina: The muscular canal extending from the cervix to the outside of the body. It is usually six to seven inches in length, and its walls are lined with mucus membrane . It includes two vaultlike structures, the anterior (front) vaginal fornix and the posterior (rear) vaginal fornix . The cervix protrudes slightly into the vagina, and it is through a tiny hole in the cervix (the os) that sperm make their way toward the internal reproductive organs. The vagina also includes numerous tiny glands that make vaginal secretions.
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Vectrin: Brand name for minocycline.
Vibramycin: Brand name for doxycycline.
Vitiligo : Pronounced vit-uh-LIE- go. A condition in which the skin turns white due to the loss of melanocytes. These cells produce melanin, the pigment that gives the skin its characteristic color. (Melanocytes also impart color to the retina of the eye and the mucous membrane tissues lining the inside of the mouth, nose, genital and rectal areas). In vitiligo, the melanocytes are mysteriously destroyed, leaving de-pigmented patches of skin on different parts of the body. The hair that grows in areas affected by vitiligo may also turn white.
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Wasting: 1. Gradual loss (for example, of weight), deterioration, emaciation. As in a wasting disease. 2. Excessive depletion. As in salt wasting, the excessive loss of salt.
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Weight loss: Weight loss is a decrease in body weight resulting from either voluntary (diet, exercise) or involuntary (illness) circumstances. Most instances of weight loss arise due to the loss of body fat, but in cases of extreme or severe weight loss, protein and other substances in the body can also be depleted. Examples of involuntary weight loss include the weight loss associated with cancer, malabsorption (such as from chronic diarrheal illnesses ), and chronic inflammation (such as with rheumatoid arthritis).
Xanax: See: Alprazolam.
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